Date Added: 13/09/2017

Date Updated: 13/09/2017

A rapid test for microbial identification in patients with suspected sepsis

Specialties: Infectious disease, microbiology & GUM

Technology Type: Diagnostics

Stage of development: Established

Stage of EAA: Assessment Complete

Description, patients and keywords:

The FilmArray Blood Culture Identification (FA-BCID) panel is a multiplex polymerase chain reaction–based rapid diagnostic test that can detect 24 sepsis-related pathogens (bacteria and yeast) and three antimicrobial resistance genes in patients with suspected sepsis.

An initial blood culture is still required, as the FA-BCID panel must be performed on blood cultures that have tested positive (indicating initial microbial growth).

The FA-BCID panel can identify specific pathogens from positive blood cultures with a turnaround time of approximately one hour; this is significantly faster than the time required to grow a full blood culture to identify pathogens.

The sensitivity and specificity of the FA-BCID panel are well established for organisms included in the panel; however, its primary limitation from a diagnostic standpoint is an inability to detect other pathogens not included in its panel.

Used along with antimicrobial stewardship programs, the FA-BCID panel may improve patient outcomes by, for example, reducing the time it takes to receive appropriate antimicrobial therapy and shortening hospital stays.