Date Added: 14/09/2017

Date Updated: 14/09/2017

MR-guided focused ultrasound (MRgFUS) for neurologic movement disorders

Specialties: Neurology & neurosurgery

Technology Type: Procedures

Stage of development: Established

Stage of EAA: Assessment Complete

Description, patients and keywords:

The Exablate Neuro™ uses magnetic resonance-guided focussed ultrasound (MRgFUS) to treat the neurologic movement disorders of essential tremor and Parkinson’s disease. MRgFUS ablation is currently in use for the treatment of uterine fibroids and bone metastases, and is under investigation in the treatment of a range of solid tumours and other conditions. The primary advantage of the Exablate Neuro is the ability to provide incisionless and non-ionising ablative surgery to brain structures, which can be precision delivered under medical imaging guidance.

The initial evidence on the use of MR guided focused ultrasound for essential tremor and Parkinson’s disease indicates that it is a safe and effective treatment in comparison to invasive deep brain stimulation. However, the long term effectiveness and risks of undergoing a neural ablative procedure are unknown due to a lack of long-term data. HealthPACT considers that further evidence, including long-term safety and effectiveness, is required.

HealthPACT does not support public investment in MRgFUS for essential tremoror Parkinson’s Disease in clinical practice at this time, and not until studies demonstrating long-term clinical utility have been published. 


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